Language: English
Duration: 37 minutes, followed by questions from the audience



Presenters: ● Prof. Mehmet Umut Akyol, Hacettepe University, Turkey

                   ● Dr. Matthias Schafer, Acura-Kliniken, Albstadt, Germany



     Part 1 - Otorhinolaryngology:

  1. Gain awareness about the main otorhinolaryngological presenting signs of mucopolysaccharidoses and Alpha-mannosidosis and their time of show-up.
  2. Recognize the challenges and dangers of surgical treatment of patients with mucopolysaccharidosis and Alpha-mannosidosis.
  3. An overview of the other Otorhinolaryngological presenting symptoms of MPS and Alpha-mannosidosis and recommendations about the timing of treatment, treatment/consultation options.

    Part 2 - Anaesthesiology:

  1. Gain awareness about the adequate perioperative workup of severe phenotype MPS-patients.
  2. Recognize the challenges and dangers of anaesthesia management of patients with MPS.
  3. An overview of main MPS symptoms influencing anaesthesia and postoperative care and recommendations for management.   



Misdiagnosis of Mucopolysaccharidosis (MPS) results in late diagnosis and the late start of treatment, which has significant consequences on long-term outcomes. This gap usually results in confusing symptoms with other conditions, most notably trying to address symptoms directly and delaying actual diagnosis and treatment or referring the patient to the wrong pediatric specialties, causing further delays in the condition’s management chain.

The Spot the Early Signs program aims to fight under-diagnosed or late-diagnosed conditions for which treatments are available and where early detection and early treatment could make a significant difference in the condition's development, the quality of life and the survival of patients.


This educational activity is designed for an international audience of General Pediatricians, General Practitioners, Pediatric Endocrinologists, Pediatric Rheumatologists, and other physicians and healthcare professionals interested in Metabolic Diseases.


Watch the video!